Huperzine A (Educational)

Acetylcholinesterase inhibition • Memory encoding

Potential Cognitive Domains

Acetylcholine Preservation

Inhibits breakdown of acetylcholine, supporting short-term memory formation and attentional control in demanding tasks.

Learning Efficiency

Enhanced cholinergic tone may improve encoding speed for novel stimulus patterns (e.g. dual n-back sequences).

Neuroprotection

Preclinical data suggests antioxidant and mitochondrial stabilizing effects; human evidence remains limited.

Dosing & Protocol

Common range: 50–200 mcg once daily.
Cycling: 2–4 weeks on, 1+ week off to mitigate tolerance.
Take early in the day to avoid vivid dreams / insomnia.

Safety Notes

Potent—microgram dosing; avoid stacking with other cholinesterase inhibitors.
Possible side effects: nausea, muscle twitching, insomnia, intense dreams.
Discontinue if GI distress or mood changes emerge.

Educational only. Not medical advice.